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We refer readers to the FY 2020 IPPS/LTCH PPS final rule (84 FR 19498 and 19499), the FY 2021 IPPS/LTCH PPS final rule (85 FR 58941), the CY 2021 PFS final rule (85 FR 84472), and the FY 2022 IPPS/LTCH PPS final rule (86 FR 45421) for our previously adopted policies regarding certification and file format requirements for hybrid measures in the Hospital IQR Program

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For mood, a meta-analysis of 26 randomized controlled trials found EPA-dominant omega-3 formulations to be superior to DHA-dominant or balanced formulations for reducing depressive symptoms, with effect sizes comparable to some antidepressant therapies [18]

Costa ND, Stevenson PM