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More importantly, the dynamic changes of biomarkers are closely related to the clinical efficacy of traditional Chinese medicine treatment, providing a modern scientific basis for the "syndrome differentiation and treatment" and "overall regulation" of traditional Chinese medicine

Tryptophan metabolism bifurcates into both toxic (IS via tryptophanase) and protective (indole-3-propionic acid via alternative pathways) branches, with the latter enhancing intestinal barrier integrity through AhR-mediated tight junction upregulation (111)

Thats how it gets regenerated back to glutathione

Hemin-induced platelet activation and ferroptosis is mediated through ROS-driven proteasomal activity and inflammasome activation: protection by melatonin