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4.3 Clinical implications: balancing benefits and risks in practice Healthcare providers should implement targeted strategies to address nutraceutical-related risks, focusing on comprehensive reviews of nutraceutical-drug interactions and the discontinuation of non-essential supplements in high-risk populations, such as the elderly or those undergoing polypharmacy (102)

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Although the mitochondrial electron transport chain (ETC) is a highly efficient system, approximately 2% of electrons may leak from the ETC and react with molecular oxygen to form the superoxide anion radical (O 2 )