In early studies, the proximity of fluorescently labeled sites on biological macromolecules was analyzed by the ensemble FRET, which provided averaged information about the distances between labeled parts of proteins
However, a study conducted by Meligi and his group, who studied the protective potential of oral administration of BV against liver damage caused by lipopolysaccharide and carbon tetrachloride in rats contradicts other reports (Meligi et al., 2020)
BPC-157 raises growth factor production (VEGF, EGF), increases collagen synthesis, promotes new blood vessel formation, protects endothelial cells, and improves blood flow
However, if the excess is too large, it will cause an increase in the acid value of the product, increase the load of water washing and purification in the later stage, and thus increase the cost