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2) It has an insulin-independent hypoglycemic effect that is related to inhibition of mitochondrial function, stimulation of glycolysis and activation of AMPK pathway

Because glutathione is exclusively synthesized in the cytosol, how glutathione enters the mitochondrial matrix remained a decades-old mystery until the recent identification that a previously uncharacterized mitochondrial metabolite transporter, SLC25A39 (A39), is critical for mitochondrial glutathione transport 13-15

We've outlined what the meeting is, what is being reviewed, and why it matters

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