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In AD, however, elevated brain iron drives microglia toward a ferroptosis-prone state, marked by upregulated heme oxygenase-1 and enhanced release of inflammatory mediators like IL-1 (140, 141)

You may also feel a little tenderness in the area for a few days

Third, dopaminergic neurons have increased vulnerability to oxidative stress because they produce a large amount of dopamine, which can be oxidized by ROS, subsequently resulting in lysosomal dysfunction and -synuclein accumulation 9

41 Similarly, in a meta-analysis of five clinical trials, vitamin D supplementation (as daily or high bolus doses, with or without calcium) was shown to reduce the risk of BPPV recurrence by 63%