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Higher gauge needles can reduce pain when injecting, but larger needles are required for injecting larger volumes of oil-based substances (like testosterone) into the muscle

Few data are available on the safety of furazolidone in pregnancy, but the Collaborative Perinatal Project monitored 50,282 mother-child pairs, and 132 had exposure to furazolidone in the first trimester with no association with congenital malformations

However, subcutaneous injection is the standard route for systemic and musculoskeletal effects, as it provides more reliable bioavailability and allows injection near the injury site