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Discussion Causality assessment and differential diagnosis We applied the Roussel Uclaf Causality Assessment Method (RUCAM) to evaluate the causal relationship between each suspected drug and DILI

It has been reported that urolithin A also increased total GSH, lowered oxidative stress, and improved cardiac function in the myocardium of diabetic rats [174]

GSH can react with HS catalyzed by sulfide quinone oxidoreductase or thiosulfate sulfurtransferase, forming GSSH, which can reduce oxidized thioredoxin

In rare cases, excess intake of certain nutrients, like potassium, could increase the risk of more serious complications, including irregular heart rhythms