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Farias ICC, Mendona-Belmont TF, da Silva AS et al (2018) Association of the SOD2 polymorphism (Val16Ala) and SOD activity with vaso-occlusive crisis and acute splenic sequestration in children with sickle cell anemia

After cooling to room temperature, 0.9 mL of 2 M NaOH, 5 mL of acetic acid, 0.1 mL of 7.5 M hydroxylamine hydrochloride, and an additional 3 mL of acetic acid were added sequentially

Kunze T, Heps S

These can include alterations in cerebral blood flow and increased intra-skull pressurecontributing substantially to damage from the initial injury. An array of resulting physical, cognitive, emotional, and behavioral symptoms often go unrecognized, especially in mild cases