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Early exposure to tobacco products predisposes individuals to addiction

European colonizers in the Americas took tobacco back to Europe as early as the 1500s

Tobacco-flavored aerosols contained the highest metal concentrations

The industry had to be seen as taking the purported risk seriously, while persistently upholding the position, More research needed. In 1953 Hill & Knowlton released their Frank Statement to Cigarette Smokers, accepting an interest in peoples health as a basic responsibility, paramount to every other consideration in our business and announcing the formation of the Tobacco Industry Research Committee (TIRC) to study the problem