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One piece of liver was fixed in 4% paraformaldehyde for liver histology and the remainder frozen in liquid nitrogen for biochemical and gene-protein expression analyses

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IS upregulates signal transducer and activator of transcription 3 (STAT3) phosphorylation, increasing production of TGF-1, monocyte chemoattractant protein-1 (MCP-1), and -smooth muscle actin (-SMA), participating in interstitial inflammation and renal fibrosis (116)

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Because BPC-157 has not been extensively studied in humans, no one knows if there is a safe dose, or if there is any way to use this compound safely to treat specific medical conditions

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In this context, the concept of molecular mimicry emerges as an innovative strategy: it is based on the design or use of biomolecules capable of imitating natural regulatory functions, such as certain peptides or lipids that mimic growth, antioxidant, or tissue repair signals

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