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The effects of two different doses of PXN (PXN LOW, PXN HIGH), CAF (CAF HIGH), and a control group on cognition (escape latency in the Morris water maze test), neurotransmitters (acetylcholine, dopamine, and gamma-aminobutyric acid), and neurochemicals (BDNF, catalase, glutathione, and cyclic GMP) were analyzed from whole brain samples in young (8 weeks old) and aged (16 months old) rats

Purification and comparison with isoenzymes isolated from adult liver and placenta

Micklefield and coworkers demonstrated the diversification of cystargolides using amide bond-forming enzymes CysC and CysD following -lactone warhead formation 37