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The survey, which was given to students across the state in the 201415 school year, asked about which tobacco and nicotine products the participants had recently used

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An important observation in this study was that the quantities of all the mentioned MMPs were greatly increased in the presence of both keratinocytes and fibroblasts, showing the importance of the crosstalk between keratinocytes and fibroblasts in MMP production, and thus the relevance of a bilayer skin model