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So while acetylcholine normally provides the just the right amount of alertness when it b inds to its receptors, nicotine produces a much more intense response (increased alertness, pleasurable feelings) due to its higher concentrations at the acetylcholine receptors

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Cigarette smoke is directly coating their mouth, throat, oesophagus and lungs with 7000 chemicals, including 69 carcinogens, and the increase in cancer risk even with light smoking is dramatic. The good news is that the risk of cancer was significantly reduced among participants who had quit smoking and the younger they quit, the better