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The positions of the other equilibria from the redox mobility shift assays in Fig

Anti-inflammatory Properties: Alleviates inflammation, reduces pain, and improves overall functioning of affected areas

The polyQ domain enables wild-type ATXN3 to interact with beclin-1, a key initiator of autophagy, allowing ATXN3 to protect beclin-1 from proteasome-mediated degradation and thereby enabling autophagy