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J Am Mosq Control Assoc 27:263271 Di Giacomo S, Mazzanti G, Di Sotto A (2016) Mutagenicity of cigarette butt waste in the bacterial reverse mutation assay: The protective effects of $$-caryophyllene and $$-caryophyllene oxide

WHO/FAO has established provisional tolerable weekly intake (PTWIs) for different toxic metals, which are 7, 25, and 5 g/kg for Cd, Pb, and total Hg, respectively 1

found that CSE resulted in inflammatory responses mediated by neutrophils and monocytes, while activated CD4+ T cells were presented in murine lungs after the prolonged exposure, implying that innate immune cells are sufficient to trigger the acute inflammation in a response to smoke stimulation [97]