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Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS

Bridging these gaps will require the integration of human-relevant models such as ovarian organoids and microphysiological systems, the development of validated biomarkers and potency assays, and the execution of large-scale, well-controlled clinical trials with long-term follow-up

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These significant decreases in total and free plasma glutathione and the redox ratio (active reduced: inactive oxidized glutathione) in children with ASD is of particular concern due to the importance of this system for normal cell function