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Binding studies show it is highly selective for mu sites , with evidence for high- and low-affinity mu subtypes that separate its analgesic and cataleptic actions [3]

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Federal officials recently suggested that the original safety signals used to justify the Category 2 placement were scientifically insufficient or lacked real-world evidence of harm

While Glu receptors generally and NMDA receptors in particular have received the lions share of attention for Spd and Spm extracellular signal transduction to date, other receptors likely exist, presenting an exciting area for future research