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Protocol details: Initial phase dose: 20-30 ml per day Initial phase route: IV infusion (diluted in 100-250 ml saline) Initial duration: 14-21 days Maintenance dose: 10 ml per day Maintenance duration: 14 additional days Infusion time: 30-60 minutes (never rapid bolus at these doses) Expected timeline based on TBI trial data: Day 7-10: Improved neurological scores on GCS Day 21: Favorable GCS in treated patients with contusion and diffuse axonal injury Week 12: Significant cognitive improvement (CASI scores) in mild TBI Month 6: 67% achieved good outcomes (GOS 3-5) in moderate to severe cases Protocol 3: combination approach with donepezil Goal: Maximize cognitive benefit in established dementia through complementary mechanisms

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Hexarelin increases cortisol by stimulating adrenocorticotropic hormone (ACTH) release, along with growth hormone

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References: Nutrients , vol

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Recalls & Warnings November 28, 2015 Herbal Supplements Linked to Heavy Metal Poisoning On November 17, 2015, Health Canada (the Canadian equivalent of the FDA) warned that a consumer in Canada who purchased and used herbal supplements from a U.S.-based website was treated for heavy metal poisoning

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