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Radiotherapy resistance in advanced PCa arises from multifactorial mechanisms, including enhanced DNA repair, cancer stem cell (CSC) persistence, immunosuppressive TME, and metabolic reprogramming [72,73]

The Regulatory Reality of 2026: What Actually Changed In late 2023, the FDA moved 19 peptides, including BPC-157, to what's known as "Category 2" status under its framework for bulk drug substances used in compounding, identifying them as substances that "may present significant safety risks." The concern, as stated in FDA guidance, centered on the limited large-scale human data and questions about immunogenicity

Supplement formats continue to evolve, and delivery methods have become just as important as the ingredients themselves

E Visualization of cell viability were evaluated by phase-contrast microscopy