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MMPs can degrade basement membrane and tight junction proteins, like occludin and claudin-5, thereby contributing to BBB damage [250]

Pharmacokinetics, dosing, and side effects have recently been reviewed in detail (P

RSL3 increased oxidized membrane lipid levels, as measured by confocal and flow cytometry using the dye C11-BODIPY in CRC DTP cells compared to the parental cells, supporting the notion of increased susceptibility of CRC persister cells to ferroptosis after 5-FU or AZ628 treatment ( Figures 3G, H )

Function [edit] Cytosolic and membrane-bound forms of glutathione S -transferase are encoded by two distinct supergene families