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This critical repair process supports much more efficient ATP (cellular energy) production, potentially raising the patient's baseline threshold for physical exertion and significantly reducing the severity, duration, and frequency of debilitating energy crashes and PEM

80,102 Very interestingly, CD38-KO mice showed increased longevity and were protected against NAD level decreases associated with age, indicating that other NAD-consuming enzymes may play an important role in age- and age-dependent diseases

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