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The in vivo study utilized naturally aged male C57BL/6 mice between 20-24 months old and young adult male C57BL/6 mice that were 3 months old

Some of the key roles of B12 in your body include: Helping in the normal functioning of the nervous system Playing a vital role in DNA synthesis B12 is among the vitamins needed in the breakdown of amino acids and fatty acids Helps in the creation and maturation of red blood cells (hemoglobin) in the bone marrow Supports the production of digestive enzymes and the delivery of essential nutrients to and from cells Its vital to the development of a fetus in pregnant women Vitamin B12 deficiency can cause different symptoms, such as fatigue, anemia, headaches, pale skin, vision problems, mouth/tongue sores, weakness, and changes in cognitive functioning

We sought a model that recapitulates features of natural aging and does not suffer from age-related pathologies caused by other processes as apoptosis(de Keizer, 2017)

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