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The minimal values of P 0 and E 0 , approximately one fourth of the control, were recorded when E

Taken together, the results of this study showed no dramatic detrimental effects of long-term cigarette smoking on the key skin barrier components suggesting that the overall barrier function in the volar forearm skin is probably not significantly compromised or the negative effects may have been compensated by the stimulation of the epidermal differentiation in the studied group of smokers

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