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A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Volixibat in the Treatment of Cholestatic Pruritus in Patients With Primary Biliary Cholangitis (2024)

Peptides in this class act at different levels of this axis: GHRH analogs (CJC-1295) stimulate the pulsatile release of GH, GHRP secretagogues (ipamorelin, GHRP-2, GHRP-6) activate ghrelin receptors, and tesamorelinthe only peptide in this class approved by the FDAincreases endogenous GH without supraphysiological effects

Team Project of the Xingzhao Talent Support Plan in Zhaotong City

These factors lead to excessive accumulation of ROS and induce lipid peroxidation, promoting the development of ferroptosis