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This conclusion is based on the findings from a six-month randomized, double-blinded, placebo-controlled trial involving 54 non-smoking adults who were assigned to receive either a placebo, 250 mg/day of GSH, or 1000 mg/day of GSH

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HPA axis studies measure serum cortisol, ACTH, and CRH levels via radioimmunoassay or ELISA following DSIP administration in stress-challenged animal models