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Among a total of 101,316, 52,730 participants were included in primary analysis (Model 1) according to the following exclusion criteria: participants aged under 18 years, participants who did not have mortality data, participants who did not respond to the questionnaire for smoking status, smoking pack years, and passive smoking (N = 48,586)

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Pierce and Stone contributed to a 2023 study in the journal Tobacco Control that said a surge in use of electronic cigarettes for vaping was independent of smoking trends. Pierce said he and other researchers aim to explore that topic further but that the focus of the latest study is exclusively on cigarette use