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(2021) 131:e140695

As one antioxidant enzyme, heme oxygenase-1 (HO-1) catalyzes heme to increase accumulation of ferrous iron, ROS production and lipid peroxidation, thereby triggers ferroptosis (Chiang et al., 2018)

The effects produced by interfering with glycolysis in OA still warrant more in-depth investigation, as is the case in cancer therapy, where inhibition of glycolysis can reduce tumor progression while causing a variety of side effects

Clinical trials for insulin sensitivity management In clinical research, scientists and physicians have explored different strategies to prevent and treat diabetes mellitus and IR