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often earlier onset, then tends to stabilise usually the best candidate for grafting Focal one or a few isolated patches that stay localised Universal very extensive (over 80%) pigment loss

Web of Science, PubMed, and Cochrane Library from September 2018 to June 2020 were systematically searched by two investigators, and the published date for searched papers from the databases ranged from June 1990 to June 2020

EDTA works by chemically binding to heavy metals present in the bloodstream, forming stable and soluble complexes that can be easily excreted through the renal system

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