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For MCI patient samples, the Petersen criteria [70] were commonly used to diagnose MCI, though other studies used revised Petersen criteria [71], or a combination of the Montreal Cognitive Assessment, DSM-IV, Clinical Dementia Rating, and Mini-Mental State Examination [34, 62]

CONCLUSION: This study suggests that SC MTX is an effective option in patients with CPP who have failed oral MTX and could be a worthwhile consideration prior to commencement of a biologic agent

38 This pain commonly presents as spontaneous burning sensations in the feet, and patients may also report positive sensory symptoms such as brush-evoked allodynia (pain from normally non-painful stimuli) and paresthesias, which are often accompanied by sensory loss, leading patients to describe the paradox of their feet being continuously painful yet insensate to touch

While these are typically only relevant in diagnostic settings, any drug affecting pituitary function or hormone levels could theoretically impact sermorelin therapy