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In preclinical studies, inhibition of glutamine synthetase has demonstrated anti-proliferative effects by disrupting glutamine-dependent pathways crucial for cancer cell survival [68]

9E), we detected increased processed LC3B (LC3B-I to LC3B-II) in HK-2 cells upon H/R and RSL3 treatment (Supplementary Fig

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Furthermore, the mechanism of APP in serum antioxidant properties was explored.The serum contains a certain amount of basal nitrite /nitrate and ROS, as well as enzymatic and non-enzymatic antioxidant systems to maintain a state of redox homeostasis 35,36