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The International Union of Pure and Applied Chemistry

Ebselen was found to increase the expression of GPX1 in SGNs after peroxynitrite damage, which is consistent with the reports that ebselen can increase the expression of GPX1 in cochlea after electrical stimulation ( gpx1 / mice leads to the aggravated SGN injury (cell loss and apoptosis) induced by peroxynitrite, although it might cause no effect on SGN development as SGNs presented normal morphology and cell number in gpx1 -deficient mice

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Structure and Biochemistry of G6PD G6PD is a ubiquitous enzyme that must be quite ancient in evolution because it has been found in all organisms, from prokaryotes to yeasts, protozoa, plants, and animals