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This led to our hypothesis that inhaling nicotine immediately prior to bedtime would lead to similar sleep disruption as conventional smoking if nicotine was the primary driver of those effects. Worse sleep in women In 274 study participants, Crotty Alexander and colleagues assessed sleep, cough and tobacco or e-cigarette use using the Pittsburgh Sleep Quality Index (PSQI), the Leicester Cough Questionnaire (LCQ) and the UCSD inhalant use questionnaire

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