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A study in older adults (average age 71 years), found an improvement vs placebo in muscle endurance 5 A 2025 study in Nature found daily 1,000 mg Urolithin A supplementation for 4 weeks improved immune function in 50 healthy middle-aged adults (ages 4570)

Navitoclax (ABT-263), another inhibitor of the BCL-2 family members, has also been used in many different studies over the years for its ability to eliminate senescent cells by inducing apoptosis

Stanton McHardy and Hua-Yu Leo Wang) at the Center for Innovative Drug Discovery, University of Texas San Antonio for the synthesis and supply of scaled batches of 5-amino-1-methylquinolinium