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10.1093/femsle/fnw270 FEMS Microbiol

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Loren Pickart first isolated this compound from human plasma in 1973 while researching why aged liver tissue could be stimulated to function like younger tissue when exposed to certain blood components

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The other two adducts, 2,3-dihydro-2-(N-formyl-2,3,6-triamino-4-oxopyrimidine-N-yl)-3-hydroxy AFB 1 and 8,9-dihydro-8-(2-amino-6-formamide-4-oxo-3,4-dihydropyrimid-5-yl formamido)-9-hydroxy AFB 1 (AFB 1 -FAPY and AFB 1 III respectively) are not spontaneously but appear to be removed catalytically by DNA repair enzymes

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Gunes Gunsel, G

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