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However, several things can inhibit the secretion of intrinsic factors, which in turn decreases the absorption of B12 by around half per dose, regardless of how high the overall dosage level is given

I stopped taking it at that point and instead started using just one a month, which seemed like it gave me a small boost at high points in training

For neurological involvement, hydroxocobalamin 1mg should be given on alternate days until no further improvement, before moving to maintenance

Phase 2b doses were 0.25 to 1.0 mg daily, which at a 2.5 mg/ml concentration means 0.1 to 0.4 ml per injection, conveniently measurable on a 1 ml insulin syringe