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We were able to restore glycolytic capacity by either incubating the cells under hypoxic conditions or treatment with Roxadustat, providing a direct link between CSE-dependent metabolic dysregulation and HIF-1 degradation under normoxia

Single laser treatment might not fully restore lip skin color, as multiple sessions are often required for optimal results, especially for conditions like melisma or vitiligo

This variation depends on several factors, including smoking patterns (such as the number of puffs and depth of inhalation), the type of cigarette smoked and individual susceptibility to the toxic substances in cigarette smoke.

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