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124 Additionally, both CBS and CSE can catalyze -substitution reactions, resulting in the condensation of two L-Cys molecules to produce H 2 S and lanthionine, or the condensation of L-Hcy and L-Cys through , -substitution reactions to produce H 2 S and cystathionine

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266 Additionally, liver-specific deletion of RNF43/ZNRF3 leads to increased levels of unsaturated lipids and the development of steatohepatitis, while also causing uncontrolled regenerative capacity following chronic damage, thereby increasing the risk of carcinogenesis