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It has shown good tolerability in both animal and early-stage human research, even at higher dose ranges

Although it is generally a temporary condition, it can place a significant amount of stress on the body, increasing the chances of developing burnout, which is a state of severe emotional, physical, and mental exhaustion that occurs if you have been under a lot of pressure for a long time

Notably, Org 24,598 has demonstrated the capacity to reduce cocaine self-administration in non-human primates following intravenous administration at 1.0 mg/kg across three experimental sessions, as well as in rodent models at intraperitoneal doses ranging from 3.0 to 7.5 mg/kg, supporting its role in attenuating cocaine-seeking behavior (Achat-Mendes et al

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