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[57] Several serious, even life-threatening diseases cause elevated serum haptocorrin, measured as abnormally high serum vitamin B 12 , while at the same time potentially manifesting as a symptomatic vitamin deficiency because of insufficient vitamin bound to transcobalamin II which transfers the vitamin to cells

The current significant caveat is that most of these data come from people at high or very high cardiovascular risk, followed for a moderate number of years

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