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In vivo , on the contrary to what was observed following the administration of bioactive end products (6-mercaptopurine and 6-thioguanine), no reduction of circulating white blood cells was observed upon administration of cAVTP and tAVTG (Gunnarsdottir et al., 2002)

According to data from the Cochrane review, administration of carnitines and combined AOX formulations had positive effect of sperm motility, and supplementation with polyunsaturated fats and zinc resulted in increase of sperm concentration ( Sperm recovery in patients with non-obstructive azoospermia A study investigated the outcome of three-month supplementation with multivitamins, micronutrients and CoQ10 in infertile men with non-obstructive azoospermia (n=24) as compared to no treatment (n=11) (104)