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25,26,27 We also previously showed that these cells exhibit low immunogenicity and exert immunosuppressive effects through PGE2-induced T-cell anergy, 28 and regulate humoral immune responses by secreting interleukin-6, which enhances B-cell viability while inhibiting B-cell proliferation, differentiation, and migration

Hence, it is one of the derivatives of the peptide found in human gastric juices

Anti-inflammatory mechanisms include modulation of inflammatory cytokines and reduction of nuclear factor-kappa B (NF-B) activity, a key inflammatory pathway

This evidence gap is the single largest limitation of peptide-based approaches