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When CD-1 IGS male mice were fed with feed containing nicotine, the mice exhibited body weight loss (19.7%), increased physical stamina and decreased respiratory exchange rate under the condition of no change in food intake, which also induced the decomposition of triglycerides in adipose tissue and weight loss

Vareniclines long track record of efficacy and safety and its approval from FDA as a smoking cessation aid favors it as the first-line choice, but this study indicates that [e-cigarettes] are certainly an option for people who are unsuccessful with or cannot tolerate varenicline, said Nancy Rigotti, director of the Tobacco Research and Treatment Center at Massachusetts General Hospital, who was not involved in the study

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