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During the 1990s and early 2000s, research interest increased in peptide fragments capable of interacting with cellular signalling systems and molecular regulatory pathways

The April 2026 withdrawal of several peptides from Category 2, including BPC-157, TB-500, and MOTS-c, opens the door for future consideration

Experimental studies demonstrate that metastatic PCa-derived EVs enhance malignant phenotypes by stimulating cancer cell proliferation, migration, and invasion while suppressing apoptosis [53]

These are stated as physiological reasoning, not as clinical screening advice, and they are not a substitute for evaluation by a qualified clinician