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In contrast, EVs derived from breast cancer cells impair pancreatic -cell function by delivering miR-122, which targets pyruvate kinase (PKM) in -cells, thereby inhibiting glycolysis and ATP-dependent insulin secretion [67]

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Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet

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