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Causes of Small-Bowel Biopsy Findings That May Mimic Celiac Disease Small intestinal bacterial overgrowth Nonsteroidal anti-inflammatory drugs Helicobacter pylori infection Giardiasis Crohn disease Viral gastroenteritis Autoimmune enteropathy Eosinophilic gastroenteritis Combined variable immunodeficiency Tropical sprue Lymphoma Zollinger-Ellison syndrome Hypersensitivity to nongluten protein Medications (olmesartan) Whipple disease is a multisystem disorder that typically occurs in White men in the fourth or fifth decade of life and can be diagnosed through polymerase chain reaction testing Treatment of Whipple disease includes intravenous antibiotics in itially and then prolonged use of oral antibiotics Tropical Sprue Features of tropical sprue may be indistinguishable from those of classic celiac disease: diarrhea, weight loss, anorexia, and lactose intolerance

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