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Among carcinogen biomarkers, DNA adducts potentially provide the most direct link to cancer, but there are still significant measurement problems

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Noticing the diplomat's bewildered and somewhat judgmental expression, the Pope smiled warmly, held out his tobacco pouch, and politely offered: "Would you care to join me in a smoke, Your Excellency?" The diplomat, drawing himself up with immense dignity, stiffly replied: "Thank you, Your Holiness, but I do not have that particular vice." Without missing a beat, Pius X smiled, took a puff from his pipe, and replied: "Ah, if it were a vice, you would undoubtedly have it."

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