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Route Topical / transdermal Published Dose Context Marketed by some clinics and compounders, but no published human exposure data was identified in FDA's December 2024 evaluation

See: Perinatal Services BC (PSBC) www.perinatalservicesbc.ca Perinatal Services BC (PSBC) provides leadership, support, and coordination for the strategic planning of perinatal services in British Columbia and is the central source in the province for evidence-based perinatal information

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In a 2-year trial involving patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risk, more events of diabetic retinopathy complications occurred in the patients treated with semaglutide injection (3%) compared to placebo (1.8%)