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They are also not approved by the FDA (Food and Drug Administration) for muscle enhancement

Conclusion: A higher burden of white matter hyperintensities in patients with vascular depression may be linked to both the progression of depressive symptoms and the severity of brain damage

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"CagriSema efficacy and safety in obesity treatment: Phase 3 REDEFINE trial results." The Lancet Diabetes & Endocrinology , 12(3), 201-213