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Probucol promotes low density lipoprotein (LDL) catabolism, inhibits ABCA1-dependent cholesterol efflux, and decreases HDL-C levels

In both MASLD and ALD, the presence of abnormal lipids can result in lipid toxicity, leading to subsequent inflammation, oxidative stress, ERS, and other related pathologies

Early human studies further suggest improvements in subjective sleep quality, daytime alertness, and overall sleep satisfaction, highlighting its potential as a targeted approach to supporting restorative sleep rather than simply increasing sleep duration

We report three major findings: (1) patients with FEP with higher GSH levels in ACC show a rapid symptom reduction upon starting antipsychotic treatment, (2) when compared with healthy controls, GSH levels in patients are dissociated from glutamate levels, and (3) Glutamate excess predicts the degree of Social and Occupational dysfunction seen at the time of presentation with FEP